Can I get a report of my sales and profit for the month without adding up every booking by hand?

Yes, you can. Travel agency software of this kind keeps a record of every booking that goes through it, whether it came from your website or was entered by your staff, so the totals are already there and you do not need to add anything up in a spreadsheet by hand. You can normally pull a report for a date range you choose, and filter it by product type such as flights or hotels, by supplier, by the staff member who made the booking, or by the sub agent who sold it.

Profit reporting works off the difference between what the supplier charged you and what you charged your customer, which means your markup rules are what the report uses to show earnings. Because of that, the figures are as accurate as the markup and fee settings you have in place, so it is worth checking those are set the way you expect before you rely on the numbers for a full month. Most reports can be exported so you can hand them to your accountant or open them in a spreadsheet.

There are honest limits. Which reports you get, and how far back you can look, can depend on your plan. Cancellations and refunds are only as complete as what the supplier has confirmed, so a refund that an airline has not yet processed may still show as pending rather than settled, and that can make one month look different until it catches up. Supplier commission that is paid to you later, rather than taken at the time of booking, usually has to be reconciled separately. This is sales reporting, not a replacement for proper accounting software.

Have a look at the reporting section of your admin panel and note which figures you actually need each month, then tell us so we can confirm what is available on your plan.